Various research applications using the adaptive solution of partial differential equations and parallel discrete event simulation as well as the investigation of object oriented programming paradigms are described. This work utilizes the IBM SP2 at Rensselaer's Scientific Computation Research Center (SCOREC). The software is designed using C, C++ and Fortran 90, together with MPI. Tools described include a parallel mesh database, load balancers and run-time code optimizers. Additionally, using plasma codes as an example, we compare compilers and architecture performance of the SP2 to competing distributed memory parallel machines. Applications studying finite element analysis of problems in biomechanics and fluid dynamics, the simulation of fusion plasma processes and the spread of Lyme disease are presented.
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